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May 10, 2021: Congratulations to Luke and Danny Orabi (Brown lab) on getting their manuscript on “A surgical method for continuous intraportal infusion of gut microbial metabolites in mice” published in JCI Insight. Danny developed a surgical technique for cannulation of the portal vein, which uses a mini pump implanted under the skin for continuous delivery of gut microbial metabolites. This method will be useful for functionally testing long-term effects of individual metabolites in mouse disease models.
April 1, 2021: We received the notice of award for the lab’s first R01! Many thanks to NIAID for supporting our plans to characterize the chemistry and biology of bacterial aryl polyene production.
March 11, 2021: Check out the updated preprint of Isabel’s paper on aryl polyene biosynthesis and role in biofilm formation.
January 18, 2021: Welcoming Rachel, a new Postdoctoral Fellow, to the team!
December 9, 2020: Congratulations to Luke for winning a Velosano Trainee Dream Experiment Fellowship!
December 4, 2020: We received a Jump Start pilot grant from the Case Comprehensive Cancer Center to study the role of the gut microbiome in modulating brain cancer development.
October 29, 2020: Danny Orabi (Brown lab) and Luke’s collaborative paper on intra-portal delivery of small molecules in mice has been posted on bioRxiv.